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There Is Nothing Left to Lose is the third studio album by American rock band Foo Fighters, released on November 2, 1999 by Roswell and RCA Records. It marked the first appearance of drummer Taylor Hawkins, and is often seen as a departure from the band's previous work, showcasing a softer, more experimental sound. Dave Grohl has stated that the album was "totally based on melody" and that it might be "[his] favorite album that [they've] ever done."

There Is Nothing Left to Lose won the Grammy Award for Best Rock Album in 2001, marking the band's first ever Grammy win. The band would go on to win the Grammy for Best Rock Album for three of their next four studio releases (One by One; Echoes, Silence, Patience & Grace; and Wasting Light).

Prior to recording, guitarist Franz Stahl was fired from the band, as frontman Dave Grohl felt the guitarist had not found his place in the band. At that point, Grohl decided that the band would just be a three piece for the record, along with bassist Nate Mendel and drummer Taylor Hawkins. Having just slaved themselves in the studio making the last record The Colour and the Shape and losing two band members in the process, he decided to buy a house in Alexandria, Virginia and make the record in its basement without any record company presence during production. This was helped by the Foo Fighters' leaving Capitol Records after president Gary Gersh left the label. Grohl named his home facility Studio 606, saying, "It's just one of those numbers that's everywhere. Like when you wake up in the middle of the night and it's 6:06, or you see a license plate that says 606." Grohl set it up with the help of Adam Kasper, who eventually co-produced the album. The biggest challenge, according to Grohl, was making the record sound good without computer programs such as Pro Tools or AutoTune.

Grohl has stated before that the band would have "a barbecue every day after recording."

The title emerged to Grohl as he talked to a friend "about when you experience these emotions after you've been through a long, difficult period and you finally give into this feeling that, quite simply, there is nothing left to lose. It can seem... positive, desperate and reckless." The frontman also said that it represented the band's mood during production: "we just wrote off and played like all bets were off. No one was forcing us to be there, so it had to be fun—and the songs had to be the best we could possibly come up with at the time."